Lost in the GophersâÄô 4-0 start to their season is the fact that the team hasnâÄôt won a single Big Ten game under coach Tim Brewster . Saturday theyâÄôll have their best chance, playing Indiana at home. Even sophomore quarterback Adam Weber , a strict disciple of the âÄúone game at a timeâÄù line, called it perhaps the teamâÄôs biggest of the year. âÄúItâÄôs going to be huge, maybe the most important game for us,âÄù he said. âÄúWeâÄôre halfway through the season, and a win is going to help us get through the rest of the season here.âÄù A win would put the Gophers (4-1, 0-1 Big Ten) just one shy of bowl eligibility with seven games left . It would also show that they can compete in the Big Ten after playing Northern Illinois, Bowling Green, Montana State and Florida Atlantic to begin the year, and losing big to Ohio State last week . âÄúWeâÄôre putting an emphasis on the conference aspect,âÄù Brewster said. âÄúItâÄôs our chance to get our first Big Ten win as a team. ThereâÄôs some significance there.âÄù The Gophers are seven point favorites over Indiana , which lost 42-20 to unranked Ball State in Week 3 and 42-29 to Michigan State last week . Of course, many thought they shouldâÄôve beat the Hoosiers (2-2, 0-1 Big Ten) last year, but the young Gophers defense gave up 249 rushing yards and 40 points. Quarterback Kellen Lewis had 75 of those rushing yards [88 excluding yards considered âÄúlostâÄù on sacks] and also threw for 235 yards . In their unique version of the spread offense, the Hoosiers will also put backup quarterback Ben Chappell in and move Lewis to a running back or wide receiver position . Brewster called Lewis âÄúa smaller versionâÄù of Ohio State true freshman quarterback Terrelle Pryor , who averaged more than 12 yards-per-carry against the Gophers on Saturday . Lewis leads the Hoosiers in rushing and is on pace for more yards than any Minnesota rusher . âÄúWe know Indiana beat us last year because we didnâÄôt do a good job against Kellen Lewis,âÄù Brewster said. âÄúFor us to have a chance, weâÄôre going to have to do a good job defending him, and not just when heâÄôs at quarterback.âÄù Both teams were in the bottom three of the Big Ten in scoring defense last year . Las Vegas odds makers put the âÄúover-underâÄù for the game, or the combination of both teamâÄôs scores, between 58 and 60 — the highest in the Big Ten this week . On top of that, Weber will be throwing against one of the most banged up secondaries in the conference, which could be missing up to three starters. Cornerback Chris Phillips suffered a season-ending knee injury against Ball State, while junior safeties Nick Polk and Austin Thomas are both questionable for the game . Polk and Thomas both missed SaturdayâÄôs game, and Hoosiers coach Bill Lynch said Tuesday he wouldnâÄôt know the status of either until âÄúlater in the week,âÄù and has not announced a status on either. Polk was not listed on the Indiana depth chart released Tuesday, while Thomas was listed as a starter .