With a weekend box office total of $23.1 million, the new Steven Soderbergh film Contagion, led all movies at the box office this weekend after opening nationwide on Friday. 

The film, with a star-studded cast consisting of Matt Damon, Gwyneth Paltrow, Kate Winslet, and others, is largely based in Minneapolis. But while the film stars Minnesota as well as the University of Minnesota Medical Center, Fairview, none of the filming actually took place within the state. 

The screenplay, written by University of Minnesota graduate Scott Z. Burns, is about a lethal virus that starts a global pandemic.